go back
- Nanoparticle-based vaccines (20-100 nm) aim to:
- Deliver the vaccine molecules to the target site
- Stimulate prolonged immune response
- Cause minimal side effects
- Require less doses for a sustained immune response
- Nanoparticle Design
- Vaccine antigens can either be:
- Decorated on the nanoparticle surface, or
- Encapsulated within the nanoparticle
- Protects the antigen from premature degradation and elicit sustainable release of antigen
- Targeting molecules e.g. antibodies, aid in delivery of particles into the antigen presenting cells (APCs) to induce innate and adaptive immune responses
